By Tibor Tot
Large-section histopathology widens your perspectives...
Correct analysis and staging are crucial in deciding upon the correct
therapy of colorectal carcinoma, probably the most universal malignancies in the US
and Europe. As scientific technological know-how maintains to advance swiftly, histopathology
remains a necessary a part of analysis in such a lot malignant ailments. during this period
of interdisciplinary medication, the function of pathology has improved to supply
images that simply correlate with endoscopic, radiological, or operative
In this amazing atlas, Tibor Tot offers colon pathology in huge
histological sections, with cross-sections of whole tumors of their anatomic
environments and their circumferential surgical margins. those specific photographs
form a advisor to analysis, tumor typing and staging based on TNM standards.
They support to evaluate the completeness of a surgical excision and to appreciate
the heterogeneity of colorectal carcinomas.
- circumstances illustrated in two-page spreads with scientific
info, traditional histopathology, and large-section histology pictures
enlarged to nearly an entire web page.
- Pathology visible within the context of surrounding tissues
- The margins of malignant tumors seen of their
- Schematic courses to interpretation of the
- Emphasis on diagnostic merits of utilizing huge
- Technical instructions for acquiring large-section histopathology specimens
This atlas is the results of seven years of learning virtually 2,000 situations of colorectal
carcinoma and different intestinal lesions and is very instructed for
pathologists, radiologists, surgeons, and oncologists alike.
Read or Download Colorectal tumors: atlas of large section histopathology PDF
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Extra resources for Colorectal tumors: atlas of large section histopathology
No preoperative irradiation. Specimen: 20-cm-long rectum with a 3 × 2-cm exophytic tumor, 4 cm from the distal margin. Adherent 6-cm-long uterus with adnexa. Histopathologic diagnosis: Moderately differentiated adenocarcinoma of the rectum, infiltrating in but not extending beyond the lamina muscularis propria, 10 lymph nodes without signs of metastasis, radical excision. Peritoneal endometriosis. TNM stage: I (T2N0M0), Dukes A. Follow-up: 22 months, no signs of disease recurrence. This large histologic section (Fig.
Endoscopically, a small suspicious lesion was found 7 cm from the anus. A preoperative diagnosis of invasive carcinoma was made on endoscopic biopsy. Surgical treatment: Mesorectal resection, no preoperative irradiation. Specimen: 22-cm-long rectum with an exophytic tumor 15 mm in diameter, 1 cm from the distal margin. Histopathologic diagnosis: Moderately differentiated rectal adenocarcinoma infiltrating into the submucosa and reaching the inner layer of the lamina muscularis propria, 13 lymph nodes without signs of metastasis, radical excision, mesorectal margin 22 mm.
10 “Early“ Rectal Carcinoma with Metastasis Fig. 10 Large-section histology image of a superficially infiltrating carcinoma of the rectum with lymph node metastasis. 11 Rectal Carcinoma, Dukes B Patient data: 59-year-old woman with rectal bleeding. A small tumor was found endoscopically in her rectum, 7 cm from the anus. The diagnosis of invasive carcinoma was made on endoscopic biopsy. Surgical treatment: Mesorectal resection, no preoperative irradiation. Specimen: 18-cm-long rectum with a 3 × 2-cm exophytic tumor, 1 cm from the distal margin.