# Accuracy of MSI testing in predicting germline mutations of by Chen S.

By Chen S.

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Example text

The one-sided alternative H : S (t) : S (t)    should be considered inappropriate. 33). Therefore, we do not reject the null hypothesis that the two survival distributions are equal. ’’ The difference between the two statements is that the error probability of the latter statement is usually much larger than that of the former. , 1979). The rats were of the same age and species and were in similar physical condition. An identical amount of tumor cells were injected into a foot pad of each rat.

In this example we limit ourselves to three distributions: the exponential, Weibull, and lognormal. In practice, more distributions may need to be considered. 7 give the hazard plots for the exponential, Weibull, and lognormal distributions, respectively. A straight line is ﬁtted to the points by eye in each of the plots. Among these graphs, the Weibull distribution appears to provide the best ﬁt to the remission data. The straight line ﬁts the points fairly closely. The estimates of  Data are used by permission of the publisher.

The median survival time decreases as age and duration of diabetes increase. Patients with a family history of diabetes, elevated fasting plasma glucose, hypertension, or retinopathy have signiﬁcantly shorter survival durations than those without these characteristics. Patients with baseline BMI values greater than or equal to 30 had much better survivorship than did patients with a lower BMI value. 36 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Patient 1 1 0 0 0 0 0 1 1 0 0 1 1 1 0 0 0 0 0 0 Status?